Laboratory device

With the new FHM 1000 series, Bosch Packaging Technology introduces semi-automated, modular laboratory devices for liquid pharmaceutical filling operations. The first prototype of the series was presented to an expert audience at the “Crailsheimer Pharmatag” in May 2013. The development is particularly suited for pharmacists and for the application in laboratories and early clinical trials. Its filling parameters can be easily scaled-up to production systems: all relevant parameters are measured and specified in the laboratory, and can then be transferred to production machines without further settings.

The FHM series significantly facilitates the design of experiments (DoE) for customers. Recording parameters makes it possible to precisely determine cause-effect relationships between influencing factors and target variables by involving customers' experience.

The laboratory device series currently consists of four different modules: the Human Machine Interface (HMI), the filling module, the weighing module and the needle movement. All automatic processes are operated from the HMI, which is the centerpiece of the laboratory device FHM 1000. The filling process with its filling needle movement and in-process control (IPC) weighing are parameterized via the HMI, whereas in- and output of the packaging is done manually.

The prototype operates with a peristaltic pump. Further filling modules are planned, for instance with a rotary slide piston pump. According to demand, the different filling systems can then be flexiblly exchanged. The integration of a closing module is also planned, enabling packaging to be equipped with different types of stoppers. A protective housing for both the filling module and the needle movement ensure product and operator safety. All modules conform to the EU Machinery Directive 2006/42/EG.